Endocrinopathies
in thalassemia - a review

Tahniyah Haq; Shapur  Ikhtaire; Farzana Rahman; Nishat  Nayla  Aurpa

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Issue: Vol.15 No.1 - January 2021

Endocrinopathies in thalassemia - a review

Authors:

Tahniyah Haq

Affiliations

Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

,

Shapur Ikhtaire

Affiliations

Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

,

Farzana Rahman

Affiliations

Department of Hematology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

,

Nishat Nayla Aurpa

Affiliations

Fulbaria Upazilla Health Complex,Fulbaria , Mymensingh, Bangladesh

Improved treatment has increased survival of patients with thalassemia. However, they still suffer from several endocrine complications mainly as a result of iron overload from multiple transfusions. Endocrinopathies manifest as early as the first decade of life, affecting growth, puberty, psychological development and quality of life. The presence of concomitant anemia, chronic liver disease and cardiomyopathy affect the development and treatment of endocrine disorders, making endocrinopathies in thalassemia a complex disorder. This review focuses on the pathogenesis, diagnosis and treatment of endocrinopathies in transfusion and non transfusion dependent thalassemia. The main points that should be considered in the management of endocrine disorders in a patient with thalassemia are highlighted in this review.

IMC J Med Sci 2021; 15(1): 008. OPEN ACCESS. DOI: https://doi.org/10.3329/imcjms.v15i1.54202

*Correspondence: Tahniyah Haq, Department of Endocrinology, Room 1620, 15th Floor, Block D, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh. Email: [email protected]